Imidazo[1,2-a]pyridine, 5-chloro-7-iodo-

Imidazo[1,2-a]pyridine, 5-chloro-7-iodo- - Names and Identifiers

Name	Imidazo[1,2-a]pyridine, 5-chloro-7-iodo-
Synonyms	5-Chloro-7-iodoimidazo[1,2-a]pyridine IMidazo[1,2-a]pyridine, 5-chloro-7-iodo- Imidazo[1,2-a]pyridine, 5-chloro-7-iodo-
CAS	1266656-98-7

Imidazo[1,2-a]pyridine, 5-chloro-7-iodo- - Physico-chemical Properties

Molecular Formula	C7H4ClIN2
Molar Mass	278.48
Density	2.13±0.1 g/cm3(Predicted)
pKa	3.80±0.50(Predicted)
Storage Condition	Room Temprature

Imidazo[1,2-a]pyridine, 5-chloro-7-iodo- - Introduction

5-Chloro-7-iodo-imidazo [1,2-a] pyridine (abbreviated CIP) is an organic compound with the chemical formula C9H4ClIN2. Its properties are as follows:

1. Appearance: CIP is a white to pale yellow crystalline solid.
2. Melting point: The melting point range of CIP is 190-192°C.
3. Solubility: CIP is insoluble in water, but soluble in organic solvents such as ethanol and dimethylformamide.

The main uses of CIP are as follows:

1. antibacterial agent: CIP has antibacterial activity and can be used as an antibacterial drug in the field of medicine.
2. pesticide: CIP is also used as a pesticide, with insecticidal, bactericidal effect.
3. laboratory reagents: CIP can be used as a reagent for organic synthesis in the laboratory.

The preparation of CIP can be carried out through the following steps:

1. 4-chloropyridine reacts with 2-iodoimidazole to generate CIP precursor.
2. The precursor is subjected to a ring-closing reaction under alkaline conditions to obtain a CIP product.
3. The product was purified and crystallized to obtain pure 5-chloro-7-iodo-imidazo [1,2-a] pyridine.

CIP security information, the following matters need to be noted:

1. toxicity: CIP has certain toxicity, should avoid direct contact with skin, eyes and mouth and nose.
2. combustion: CIP in heating or fire will produce toxic gases and smoke, need to avoid contact with open flame.
3. Storage: CIP should be stored in a dry, well-ventilated place, away from fire and oxidant.

Last Update：2024-04-09 21:21:28